Tehran University of Medical Sciences
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Maryam Zahmatkesh

Contact Information
http://medicine.tums.ac.ir/default.aspx?p=1726
Tel: 02143052155
Fax: 02188991117
Address: Neuroscience Department, School of Advanced Medical Technologies, Tehran University of Medical Sciences,/Ghods Street, Italia St
Academic Rank
Professor
School
Advanced Technologies in Medicine
Neuroscience
About
CV last edited on: 2020/18/11

1.

Ph.D


PhD of Medical Physiology , Tehran University of Medical Sciences, Tehran, IRAN, 2001-2005
2.

M.Sc


MSc of Medical Physiology , Shiraz University of Medical Sciences, Shiraz, IRAN, 1998-2001
1.

English


Speaking: Good, Reading: Good, Writing: Good
1.

Young Investigator Award in 10th Congress of The Middle East Society For Organ Transplantation, Kuwait


2006,

Scientific Position

1.

Associate Professor of Physiology


at Tehran University of Medical Sciences,

Executive Position

1.

EDO member


at School of Advanced Technologies in Medicine,
2.

Neuroscience Board member


At Ministry of Health and Medical Education,

Ph.D

1.

Neurophysiology


2Unit, School of Advanced Technologies ,Ph.D.
2.

Neuroendocrinology


2Unit, School of Advanced Technologies ,Ph.D.
3.

Neurobiology


2Unit, School of Advanced Technologies ,Ph.D.
1.

Simvastatin adminestration in a rat model of streptozotocin-induced experimental dementia of Alzheimer's type


Status: Running, Executers: Zahmatkesh M, Sponser: Vice Chancellor for Research, Location: Code: 92-03-87-24462,
2.

Study of alteration in plasma-oxidative indices at opioid-addicted persons refered to NOOR’s Substance Abuse Treatment Centers during the first two week of methadone maintenance therapy and evaluation of their relations with the Matrix Metalloproteinase-9 activity and TNF-α concentration


Status: Running, Executers: Zahmatkesh M, Kadkhodaee M, Sponser: Vice Chancellor for Research, Location: Code: 92-03-87-24225, 1392-1394
3.

An elective integrated module of nanotechnology applications in neuroscience for PhD students at neuroscience department: Design and Implementation


Status: Completed, Executers: Zahmatkesh M, Faridi-Majidi R, Ejtemaee-Mehr Sh, Zarrindast MR, Sponser: EDC, Location: Code: 91-04-87-20050, آذر 91
4.

Kinetic assessment of Platelet and Endotelial Microparticles in a rat model of streptozotocin-induced experimental dementia of Alzheimer's type


Status: Completed, Executers: M. Zahmatkesh, Sponser: Vice Chancellor for Research, Location: Code: 89-04-87-11736, 1389-1392
5.

Evaluation of endogenous ouabain in Alzheimer model induced with intracerebral infusion of streptosozine in male rat


Status: Completed, Executers: M. Zahmatkesh, Sponser: Vice Chancellor for Research, Location: Code: 89-01-87-10377, 2010-2011
6.

An integrated special study module of basal nuclei for undergraduate medical students: Design and Implementation


Status: Completed, Executers: M. Zahmatkesh, Sponser: Vice Chancellor for Research, Location: Code: 87-03-7827, 2006-2007

Supervisor

1.

Assessment of lipophilic fluorescent products in Alzheimerʹ model induced by β amyloid


,
Ph.D, Neuroscience,
2.

Study of possivble nuroprotective effects of histone deacetylase class IIB inhibition on β- amyloid treated male rats


,
Ph.D, Neuroscience,
3.

Effect of GnRH on dorsal Hippocampal estradiol


,
Ph.D, Neuroscience,
4.

Effect of melatonin on mitochondria biogenesis in Amyloid Beta(25-35)-induced cognitive decline


,
Ph.D, Neuroscience,
5.

Study of Apelin-neuroprotective mechanism in a rat model of intracerebroventricular injection of Aβ


,
Ph.D, Neuroscience,
6.

Investigation of changes in microparticles after methamphetamine exposure


,
Ph.D, Addiction Studies,
7.

Effect of Simvastatin in rat model of streptozotocin-induced experimental dementia of Alzheimer


,
Ph.D, Neuroscience,
8.

Study of plasma oxidative parameters alteration in MMT and its relation with MMP-9 and TNF-a


,
Ph.D, Addiction studies,
9.

Effects of galvanic vestibular stimulation on spatial memory in a rat model of streptozotocin-induced experimental sporadic dementia of Alzheimer's type


,
Ph.D, Audiology,
10.

Kinetic assessment of Platelet and Endotelial Microparticles in a rat model of streptozotocin-induced experimental dementia of A


,
Ph.D, Neuroscience, 2010-2012
11.

Effects of liver ischemia-reperfusion injury on renal function, oxidative status and histology


,
M.Sc, Medical Physiology, 2008-2009
12.

Evaluation the effect of non-ischemic uremia on liver in total nephrectomy model in male rat: Comparison with the ischemic uremi


,
Ph.D, Medical Physiology, 2007-2009
13.

Evaluation of sperm superoxide production and mitochondrial membrane potential by flow-cytometry in rat with experimental varico


,
M.Sc, Medical Physiology, 2007-2008
14.

Evaluation of blood antioxidant levels and alterations of calcium and pH in hemodialytic patients, Imam Hospital


,
M.Sc, Medical Physiology, 2005-2006

Farsi

1.

Neuroendocrinology


Authors: زحمتکش مریم، شفیعی ثابت مهدی، ......
فارسی, Publisher: انتشارات ابن سینا, 1397, اول, تالیف
2.

Integrated training of basal ganglia


Authors: حسن زاده غلامرضا، اجتماعي مهر شهرام، زحمتكش مریم، سيديان مازيار، اربابي محمد، ميرزازاده عظیم
فارسی, Publisher: انتشارات ابن سینا, 1390, اول, تالیف
3.

Renal Physiology


Authors: كدخدايي مهري، خواستار حسين، زحمتكش مريم
فارسی, Publisher: طراحان پديده چاپ, 1383, اول, تالیف

Papers

English

1.

GnRH protective effects against amyloid β-induced cognitive decline: A potential role of the 17β estradiol


Authors: Marbouti L, Zahmatkesh M, Riahi E, Sabet MS.
Molecular and Cellular Endocrinology, Year. 2020,
2.

Inhibition of brain 17β-estradiol synthesis by letrozole induces cognitive decline in male and female rats


Authors: Marbouti L, Zahmatkesh M, Riahi E, Sadr SS,
Neurobiology of Learning and Memory, Year. 2020,
3.

Anxiolytic Impact of Apelin-13 in a Rat Model of Alzheimer's Disease: Involvement of Glucocorticoid Receptor and FKBP5


Authors: Aminyavari S, Zahmatkesh M, Khodagholi F, Sanati M
Peptides, Year. 2019,
4.

Simvastatin Attenuates Hippocampal MMP-9 Expression in the Streptozotocin-Induced Cognitive Impairment.


Authors: Adeli S, Zahmatkesh M, Dezfouli M.
Iran Biomed J, Year. 2019,
5.

Melatonin protective effect against amyloid β-induced neurotoxicity mediated by mitochondrial biogenesis; involvement of hippocampal Sirtuin-1 signaling pathway


Authors: Ansari Dezfouli M, Zahmatkesh M, Farahmandfar M, Khodagholi F
Physiology & Behaviour, Year. 2019,
6.

Protective role of Apelin-13 on amyloid β25–35-induced memory deficit; Involvement of autophagy and apoptosis process


Authors: Aminyavari S, Zahmatkesh M, Farahmandfar M, Khodagholi F, Dargahi L, Zarrindast MR
Progress in Neuro-Psychopharmacology and Biological psychiatry, Vol.89, Year. 2019, Page:322-334,
7.

Effect of methamphetamin exposure on the plasma levels of endothelial-derived microparticles


Authors: Nazari A, Zahmatkesh M, Mortaz E, Hosseinzadeh S
Drug and Alcohol Dependency, Year. 2018,
8.

Opioid Use Disorder Induces Oxidative Stress and Inflammation: The Attenuating Effect of Methadone Maintenance Treatment


Authors: 4. Salarian A, Kadkhodaee M, Zahmatkesh M, Seifi B, Bakhshi E, Akhondzadeh Sh, Adeli S, Askari H, Arbabi M.
Iran J Psychiatry, Vol.13, No.1, Year. 2018, Page:46-54,
9.

Impact of opioids on oxidative status and related signaling pathways: An integrated view


Authors: Maryam Zahmatkesh, Mehri Kadkhodaee, Ali Salarian, Behjat Seifi , Soheila Adeli
Journal of Opioid Management, Year. 2017,
10.

Simvastatin enhances the hippocampal Klotho in a rat model of streptozotocin-induced cognitive decline


Authors: 1. Soheila A, Zahmatkesh M, Tavoosidana GR, Karimian M, Hassanzadeh GR
Progress in Neuro-Psychopharmacology & Biological Psychiatry, Year. 2016,
11.

Noisy galvanic vestibular stimulation enhances spatial memory in cognitive impairment-induced by intracerebroventricular-streptozotocin administration


Authors: Adel Ghahraman M, Zahmatkesh M, Pourbakht A, Seifi B, Jalaie S, Adeli S, Niknami Z
Physiology & Behavior, Year. 2016,
12.

Curcumin as a double-edged sword for stem cells: dose, time and cell type-specific responses to curcumin


Authors: Attari F, Zahmatkesh M, Aligholi H, Mehr SE, Sharifzadeh M, Gorji A, Mokhtari T, Khaksarian M, Hassanzadeh G
Daru. Journal of Pharmaceutical Sciences, Vol.23, No.12, Year. 2015,
13.

Hippocampal DHCR24 down regulation in a rat model of streptozotocin-induced cognitive decline


Authors: Hosseinzadeh S, Zahmatkesh M, Heidari M, Hassanzadeh GR, Karimian M, Sarrafnejad A, Zarrindast MR
Neuroscience Letters, Year. 2015,
14.

Trimetazidine prevents oxidative changes induced in a rat model of sporadic type of Alzheimer΄s disease


Authors: Hassanzadeh GR, Hosseini A, Pasbakhsh P, Akbari M, Ghaffarpour M, Takzare N, Zahmatkesh
Acta Medica Iranica , Year. 2015,
15.

Angiotensin II in paraventricular nucleus contributes to sympathoexcitation in renal ischemia reperfusion injury by AT1 receptor and oxidative stress


Authors: Seif B, Kadkhodaee M, Bakhshi E, Ranjbaran M, Zahmatkesh M, Sedaghat Z, Ahghari P, Esmaeili P
Journal of Surgical Research, Year. 2014, Page:1-7,
16.

Elevated CSF and plasma microparticles in a rat model of streptozotocin-induced cognitive impairment


Authors: Hosseinzadeh S, Zahmatkes M, Zarrindast MR, Hassanzadeh GR, Karimian M, Sarrafnejad A.
Behavioural Brain Research, Year. 2013,
17.

Evaluation of functional relationship between mouse hippocampal cholinergic and nitrergic systems in anxiogenic-like behavior


Authors: Zarrindast MR, Piri M, Bananej M, Shahab Z, Zahmatkesh M
Behavioural Pharmacology, Year. 2013,
18.

Modulation of ventral tegmental area dopamine receptors inhibit nicotine-induced anxiogenic-like behavior in the central amygdala


Authors: Zarrindast MZ, Eslahi N, Rezayof A, Rostami P, Zahmatkesh M
Progress in Neuro-Psychopharmacology & Biological Psychiatry, Vol.41, Year. 2013,
19.

Involvement of rat dopaminergic system of nucleus accumbens in nicotine-induced anxiogenic-like behaviors


Authors: Zarrindast MZ, Khalifeh S, Rezayof A, Rostami P, Aghamohammadi Sereshki A., Zahmatkesh M
Brain Research , Vol.1460, Year. 2012, Page:25-32,
20.

Alteration of renal functional, oxidative stress and inflammatory indices following hepatic ischemia-reperfusion


Authors: 2. Kadkhodaee M, Mikaeili S, Zahmatkesh M, Golab F, Seifi B, Arab HA, Shams S, Mahdavi-Mazdeh
Gen. Physiol. Biophys, Vol.31, Year. 2012,
21.

Evaluation of vitamin E therapy on serum uric acid in DOCA-Salt treated rat


Authors: Seifi B, Kadkhodaee M, Zahmatkesh M
Acta physiologica Hungarica , Vol.98, Year. 2011, Page:208-214,
22.

.Medical students' viewpoint regarding the integrated module of basal ganglia


Authors: Ejtemaee-mehr S., Hassanzadeh G., Zahmatkesh M, Seyedian M., Arbabi M., Mirzazadeh A., Hatami F
Acta Medica Iranica , Vol.49, Year. 2011, Page:753-759,
23.

Antioxidative status in the early post-transplant period: Cyclosporine A vs Sirolimus-based regimens


Authors: Nafar M, Kadkhodaee M, Mahdavi-Mazdeh M, Zahmatkesh M, Seifi B, Ghaznavi R
International Journal of Nephrology Urology, Vol.2, No.2, Year. 2010, Page:330-334,
24.

Hypertension, pro-inflammatory cytokines in vasculature and oxidative stress in kidney in rats on DOCA-salt treatment


Authors: Seifi B, Kadkhodaee M, Karimian M, Zahmatkesh M, Jie Xu, Soleimani M
. Clinical and Experimental Hypertension, Vol.32, No.2, Year. 2010, Page:90-97,
25.

The synthesis and antifertility evaluation of three analogues of pyrimethamine on male rat reproductive indices


Authors: Sadeghipour HR, Vosooghi M, Sattarian M, Zahmatkesh M, Noori S MH
Reproductive, Vol.17, No.8, Year. 2010, Page:748-753,
26.

Flowcytometric evaluation of sperm superoxide anion production in rat with experimental varicocele


Authors: Jafari A, Zahmatkesh M, Sadeghipour HR, Kajbafzadeh AM, Sarrafnejd A, Shahrestany ST, Noori SM
Urology, Vol.75, Year. 2010, Page:217-222,
27.

Oxidative stress status in renal transplant recipients


Authors: Zahmatkesh M, Kadkhodaee M, Mahdavi-Mazdeh M, Ghaznavi R, Hemati M, Seifi B, Golab F, Hasani K, Lessan-Pezeshki M, Einollahi B
Experimental and Clinical Transplantation, Vol.1, Year. 2010, Page:38-44,
28.

Effects of different periods of renal ischemia on liver as a remote organ


Authors: Kadkhodaee M, Golab F, Zahmatkesh M, Ghaznavi R, Hedayati M, Arab HA, Ostad SN, Soleimani M
World Journal of Gastroenterology, Vol.15, No.9, Year. 2009, Page:1113-1118,
29.

Changes in Serum and Renal Vitamin E Levels in Deoxycorticosterone Acetate–Salt Hypertensive Rats


Authors: Seifi B, Kadkhodaee M,Zahmatkesh M, Golab F, Bakhshi E
Transplantation Proceedings , Vol.41, Year. 2009, Page:2910-2911,
30.

Hepatic Changes During Various Periods of Reperfusion After Induction of Renal Ischemia in Rats


Authors: Golab F, Kadkhodaee M, Zahmatkesh M, Ghaznavi R,Arab H,Seifi B and Soleimani M
Transplantation Proceedings, Vol.41, Year. 2009, Page:2749-2750,
31.

. Ischemic and Non ischemic acute renal failure induce hepatic injury


Authors: Golab F, Kadkhodaee M, Zahmatkesh M, Hedayati M, Arab H, Schuster R, Zahedi K, Lentsch AB, Soleimani M
Kidney International, Vol.75, Year. 2009, Page:783-792,
32.

. Proteinuria Is Reduced by Inhibition of Inducible Nitric Oxide Synthase in Rat Renal IR Injury


Authors: . Kadkhodaee M, Zahmatkesh M, Sadeghipour HR., Eslamifar A, Taeb J, Shams A, Mahdavi-Mazdeh M
Transplantation Proceedings , Vol.41, Year. 2009, Page:2907-2909,
33.

. Reduction of Kidney Damage by Supplementation of Vitamins C & E in Rats with DOCA-Salt-Induced Hypertension


Authors: Seifi B, Kadkhodaee M,Karimian M, Zahmatkesh M, Shams S,Bakhshi E
Iranian Journal of Kidney Disease, Vol.3, Year. 2009, Page:197-202,
34.

Effect of bicarbonate administration on cyclosporin A-induced rat nephrotoxicity


Authors: Zahmatkesh M, Kadkhodaee M, Seifi B, Sham S
Transplantation Proceedings , Vol.41, Year. 2009, Page:2905-2906,
35.

Assessment of plasma antioxidant status in HD patients


Authors: Kadkhodaee M, Hemmati M, Zahmatkesh M, Ghaznavi R, Mirershadi F, Mahdavi-Mazde M, Seifi B
Therapeutic Apheresis and Dialysis, Vol.12, No.2, Year. 2008, Page:147-151,
36.

Antioxidant vitamins preserve superoxide dismutase activities in gentamicin induced nephrotoxicity


Authors: Kadkhodaee M, Khastar H, Arab HA, Ghaznavi R, Zahmatkesh M, Mahdavi-Mazdeh M
Transplantation Proceedings, Vol.39, Year. 2007, Page:864-865,
37.

Cyclosporine effects on the antioxidant capacity of rat renal tissues


Authors: Ghaznavi R,Zahmatkesh M, Kadkhodaee M, Mahdavi-Mazdeh M
Transplantation Proceedings, Vol.39, Year. 2007, Page:866-867,
38.

. Acid-base status determines cyclosporine A-induced hypercalciuria


Authors: Zahmatkesh M, Kadkhodaee M, Ghaznavi R, Mahdavi-mazdeh M.
Transplantation Proceedings, Vol.39, Year. 2007, Page:1231-1232,
39.

Effects of co-administration of an iNOS inhibitor with a broad spectrum reactive species scavenger, in rat renal ischemia/reperfusion injury


Authors: Zahmatkesh M, Kadkhodaee M, Arab HA, Shams S
Nephron Experimental Nephrology, Vol.103, Year. 2006, Page:119-125,
40.

Effects of co-supplementation of vitamin E and C on rat gentamicin nephrotoxicity


Authors: Kadkhodaee M, Khastar H, Faghihi M, Ghaznavi R, Zahmatkesh M
Exprimental Physiology , Vol.90, Year. 2005, Page:571-576,
41.

Beneficial effects of MnTBAP, a broad spectrum reactive species scavenger, in rat renal ischemia/reperfusion injury


Authors: Zahmatkesh M, Kadkhodaee M, Moosavi SM, Jorjani M, Kajbafzadeh A, Golestani A, Ghaznavi R
Clinical and Experimental Nephrology , Vol.9, Year. 2005, Page:212-218,
42.

Protection of rat renal vitamin E levels by ischemic-preconditioning


Authors: Kadkhodaee M, Aryamanesh S, Faghihi M, Zahmatkesh M
BMC Nephrology , Vol.5, Year. 2004, Page:1-8,
1.

Auditory and Vestibular Research


Editorial Board Member,
2.

Iranian Journal of Neurology


Editorial Board Member,
1.

HPLC analysis protocol


2.

Well familiar with Flowcytometry technique


3.

Well familiar with electrophysiology recording


4.

Well familiar with recoding through the PowerLab data acquisition system


1.

Membership in Iranian Society of Physiology and Pharmacology from 2003


Activity Type:Member
2003
1.

Educational fellowship at Educational Development Center, TUMS, 2007


1. Neurohormonal changes in aging and Alzheimer's disease
2. Kinetic assessment of Microparticles in Alzheimer's disease
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