Tehran University of Medical Sciences
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Mehdi Akhlaghi

Contact Information
Fax: 02188026905
Address: Tehran, TUMS.Shariati Hospital, Research Center for Nuclear Medicine
Academic Rank
Assistant Professor
Hospital
Shariati
Research Center
Research Institute for Nuclear Medicine
About
CV last edited on: 2019/30/09

1.

Ph.D


شیمی محض (آلی), دانشگاه صنعتی شریف, تهران, ایران, 1391
2.

M.Sc


شیمی محض (آلی), دانشگاه صنعتی شریف, تهران, ایران, 1382
3.

B.Sc


شیمی محض, دانشگاه ارومیه, ارومیه, ایران, 1379
1.

Azeri


Speaking: Native, Reading: Native, Writing: Native
2.

Persian


Speaking: Native, Reading: Native, Writing: Native
3.

English


Speaking: Medium, Reading: Good, Writing: Good
1.

Labeling of chitosan with 111In, quality control of product and investigation of distribution and therapeutic effects on the cancerous tissues of mouse by administration directly to the lesion


Status: Completed, Executers: Mehdi Akhlaghi, Sponser: ثبت شده در سازمان انرژی اتمی(NRCAM-85-11-163 شماره طرح), Main Partners: Jalilian, A. R., Rowshanfarzad, P., Moradkhani, S., Kamalidehghan, M., Saddadi, F., Ardaneh, K., Mirzaii, M., Pooladi, M., ,
2.

presenting an improved radiochemical method for FDG to increase the yield, decreasing the synthesis time and its quality control.


Status: Completed, Executers: Mehdi Akhlaghi, Sponser: ثبت شده در سازمان انرژی اتمی (NRCAM-85-9-160 شماره طرح)., Main Partners: Mirzaii, M., Aslani, G.R., Pooladi, M., Ardaneh. K.,,
3.

Design and fabrication of [11C] CO2 production system


Status: Completed, Sponser: ثبت شده در سازمان انرژی اتمی (NRCAM-87-01-180 شماره طرح), Main Partners: Aslani, G. R., Rafiei, H., Rowshanfarzad, P., Akhlaghi, M., Ensaf, M.R., Safari, F., ,
4.

Design and construction of Co-57 production system.


Status: Completed, Sponser: ثبت شده در سازمان انرژی اتمی (NRCAM-84-12-140 شماره طرح), Main Partners: Roshanfarzad, P., (person in charge), Moafian, J., Ensaf, M. R., Akhlaghi, M., Sabet, M., Aslani, G.R., Jalilian, A.R., Rajabifar, S., ,
5.

Design and fabrication of prototype standard sealed point sources and sealed plastic vials from the 57Co radioisotope produced in the cyclotron and nuclear medicine department


Status: Completed, Executers: Sabet M, Sponser: ثبت شده در سازمان انرژی اتمی (NRCAM-85-9-162 شماره طرح, Main Partners: Sabet, M., (person in charge), Rowshanfarzad, P., Akhlaghi, M., Jalilian, A.R., Reisali, G.R., Safari, F., Fathollahi, H., Aalipoor, A., Moafian, J., ,
6.

Production of [18F]FTHA for kinetic study of myocardial


Status: Completed, Executers: Jalilian, A. R., , Sponser: ثبت شده در سازمان انرژی اتمی (NRCAM-85-6-153 شماره طرح), Main Partners: Jalilian, A. R., (person in charge), Akhlaghi, M., Mirzaii, M., Rajabifar, S., Kamilidehghan, M., Daneshvari, S., Saddadi, F., Pooladi, M., Shirazi, B., Ensaf. M.R,

Papers

English

1.

Chelator-free radiolabeling of dextran with 68Ga for PET studies


[Chelator-free radiolabeling of dextran with 68Ga for PET studies]
Authors: Gholipour, N., Akhlaghi, M., Kheirabadi, A.M., Beiki, D., Geramifar, P., Yousefnia, H., Mazidi, M.
Journal of Radioanalytical and Nuclear Chemistry, Vol.9, Year. 2017, Page:1-7,
2.

Production of 68Ga-citrate based on a SnO2 generator for short-term turpentine oil-induced inflammation imaging in rats


Authors: Mirzaei, Alireza and R Jalilian, Amir and Akhlaghi, Mehdi and Beiki, Davood
Current radiopharmaceuticals, Vol.9, Year. 2016, Page:208--214,
3.

Development of 68Ga ethyl cysteinate dimer for PET studies


Authors: Mirzaei, Alireza and Jalilian, Amir R and Shabani, Gholamali and Fakhari, Ashraf and Akhlaghi, Mehdi and Beiki, Davood
Journal of Radioanalytical and Nuclear Chemistry, Vol.307, Year. 2016, Page:725--732,
4.

Preparation and radiolabeling of a lyophilized (kit) formulation of DOTA-rituximab with 90 Y and 111 In for domestic radioimmunotherapy and radioscintigraphy of Non-Hodgkin’s Lymphoma


Authors: Gholipour, Nazila and Jalilian, Amir Reza and Khalaj, Ali and Johari-Daha, Fariba and Yavari, Kamal and Sabzevari, Omid and Khanchi, Ali Reza and Akhlaghi, Mehdi
DARU Journal of Pharmaceutical Sciences, Vol.22, Year. 2014, Page:58,
5.

HPLC ANALYSIS OF RADIOGALLIUM LABELED PROTEINS USING A TWO-SOLVENT SYSTEM


Authors: Jalilian, Amir R and Akhlaghi, Mehdi
Journal of Liquid Chromatography \& Related Technologies, Vol.36, Year. 2013, Page:731--739,
6.

Development of Radiolabeled Recombinant Erythropoietin for Receptor Studies


Authors: Jalilian, AR and Sadeghpour, H and Akhlaghi, M and Gholami, E
Journal of Nuclear Science and Technology, Year. 2012, Page:73--79,
7.

Lethality Assay of Radiopharmaceutical bis-Thiosemicarbazones Using Brine Shrimp (Artemia salina) Test


Authors: Jalilian, Amir Reza and Novinrooz, Aytak and Sadraee, Sahar and Heydarieh, Marzieh and Akhlaghi, Mehdi
Iranian Journal of Pharmaceutical Sciences, Vol.8, Year. 2012, Page:197--201,
8.

Development of Sm-153 Chitosan for Radiosynovectomy


Authors: Samani, AB (Samani, A. Bahrami); Jalilian, AR (Jalilian, A. R.); Yousefnia, H (Yousefnia, H.); Akhlaghi, M (Akhlaghi, M.); Mazidi, M (Mazidi, M.); Ghannadi-Maragheh, M (Ghannadi-Maragheh, M.)
European Journal of Nuclear Medicine and Molecular Imaging, Vol.38 , No. 2, Year. 2011, Page:S303-S304 ,
9.

Preparation and evaluation of a [66Ga] gallium chitosan complex in fibrosarcoma bearing animal models


Authors: Pourjavadi, Ali and Akhlaghi, Mehdi and Jalilian, Amir R
Nukleonika, Vol.56, Year. 2011, Page:35--40,
10.

Preparation and primary evaluation of 66Ga-DTPA-chitosan in fibrosarcoma bearing mice


Authors: Akhlaghi, Mehdi and Pourjavadi, Ali
Nukleonika, Vol.56, Year. 2011, Page:41--47,
11.

Development of Sm-153 Chitosan for Radiosynovectomy


Authors: Jalilian, Amir Reza and Yousefnia, Hassan and Bahrami-Samani, Ali and Ghannadi-Maragheh, Mohammad and Mazidi, Mohammad and Akhlaghi, Mehdi
Iranian Journal of Nuclear Medicine, Vol.1, Year. 2010, Page:22--31,
12.

Possibility of production of a novel radiopharmaceutical for identification of hypoxic tissues


Authors: Rostampour, Nima and Jalilian, Amir Reza and Tavakkoli, Mohammad Bagher and Shafei, Kamaleddin and Kamali Dehghan, Mohsen and Akhlagh, Mehdi and Ghazikhanloo Ghazi, Karim
پژوهش در پزشکی, Vol.34, No.Rostampour, Nima and Jalilian, A, Year. 2010, Page:89--106,
13.

Preparation and biological evaluation of [67 Ga]-labeled-superparamagnetic iron oxide nanoparticles in normal rats


Authors: Jalilian, AR and Panahifar, A and Mahmoudi, MORTEZA and Akhlaghi, MAHDI and Simchi, A
Journal of Nuclear Science and Technology, Year. 2010, Page:29--36,
14.

Preparation of [6l Cu] Bleomycin Complexes as a Potential PET radiopharmaceutical and it's biological evaluation in normal and tumor-bearing rodents


Authors: Jalilian, AMIR REZA and Zandi, HASAN and Akhlaghi, MAHDI and Kamali Dehghan, M and Bolourinovin, F and Moradkhani, SEDIGHEH and Majdabadi, A
Journal of Nuclear Science and Technology, Year. 2010, Page:9--17,
15.

Preparation and primary evaluation of 66Ga-DTPA-chitosan in fibrosarcoma bearing mice via intra-tumor injection technique


Authors: Akhlaghi, Mehdi and Pourjavadi, Ali and JALILIAN, AMIR REZA
Nukleonika, Year. 2010,
17.

Production and quality control of 166Ho-Chitosan for therapeutic applications


Authors: Zolghadri, Samaneh and Jalilian, Amir Reza and Yousefnia, Hassan and Bahrami-Samani, Ali and Shirvani-Arani, Simindokht and Mazidi, Mohammad and Akhlaghi, Mehdi and Ghannadi-Maragheh, Mohammad
Iranian Journal of Nuclear Medicine, Vol.18, Year. 2010, Page:1--8,
18.

Comparison of the effect of chamfer and radial shoulder finish line designs on marginal adaptation ofAll-ceramic Cercon restorations


Authors: Jalalian, E and Mirtorabi, M
Journal of Dental Medicine, Vol.23, Year. 2010, Page:147--152,
19.

Erratum: Production and biological evaluation of [201Tl (III)] bleomycin


Authors: Jalilian, Amir R and Aboudzadeh, Reza and Akhlaghi, Mehdi and Shirazi, Behrooz and Moradkhani, Sedighe and Salouti, Mojtaba and Karimian, Alireza and Babaii, Mohammad H and Raisali, Gholamreza
Journal of Labelled Compounds and Radiopharmaceuticals, Vol.53, Year. 2010, Page:214--214,
20.

Radiosynthesis and evaluation of [61Cu]-9, 10-phenanthrenequinone thiosemicarbazone in fibrosarcoma-bearing animals for PET imaging


Authors: Jalilian, AR and Emami, Azamolsadat and Akhlaghi, M and Kamali-dehghan, M and Shafaii, Kamaledin and Moradkhani, Sedigheh
Radiochimica Acta International journal for chemical aspects of nuclear science and technology, Vol.98, Year. 2010, Page:175--181,
21.

Development of [111In]-DTPA-buserelin for GnRH receptor studies


Authors: Jalilian, AR and Shanehsazzadeh, Saeed and Akhlaghi, M and Kamali-Dehghan, M and Moradkhani, Sedigheh
Radiochimica Acta International journal for chemical aspects of nuclear science and technology, Vol.98, Year. 2010, Page:113--119,
22.

P125 PREPARATION AND BIOLOGICAL EVALUATION OF [67Ga]-LABELED-SUPERPARAMAGNETIC NANOPARTICLES IN NORMAL RATS


Authors: PANAHIFAR, A and JALILIAN, AR and AKHLAGHI, M and ZANDI, H
Journal of Labeled compound and radiopharmaceuticals, Year. 2009,
23.

Preparation and biological evaluation of [67Ga]-labeled-superparamagnetic nanoparticles in normal rats


Authors: Jalilian, Amir R and Panahifar, A and Mahmoudi, M and Akhlaghi, M and Simchi, A
Radiochimica Acta International journal for chemical aspects of nuclear science and technology, Vol.97, Year. 2009, Page:51--56,
24.

Radiosynthesis and biodistribution of [18 F]-tetracosactide using a semi-automated [18 F] SFB production module


Authors: Akhlaghi, Mehdi and Ahi, Leyla Pashaye and Jalilian, Amir Reza and Garousi, Javad and Pour-Heravi, Mohammad Reza Abdolrahim
Nuclear Science and Techniques, Vol.20, Year. 2009, Page:163--169,
25.

Preparation, quality control and biodistribution of [61Cu]-doxorubicin for PET imaging


Authors: Jalilian, Amir Reza and Yousefnia, Hassan and Faghihi, Reza and Akhlaghi, Mehdi and Zandi, Hassan
Nucl. Sci. Tech, Vol.20, Year. 2009, Page:157--162,
26.

A new eco-friendly and efficient mesoporous solid acid catalyst for the alkylation of phenols and naphthols under microwave irradiation and solvent-free conditions


Authors: Moghaddam, F Matloubi and Akhlaghi, M and Hojabri, L and Dekamin, MG
Scientia Iranica. Transaction C, Chemistry, Chemical Engineering, Vol.16, Year. 2009, Page:81,
27.

Preparation and biological evaluation of a [55Co]-2-acetylpyridine thiosemicarbazone


Authors: Jalilian, Amir R and Rowshanfarzad, Pejman and Akhlaghi, Mehdi and Sabet, Mahsheed and Kamali-Dehghan, Mohsen and Pouladi, Mehrban
Scientia Pharmaceutica, Vol.77, Year. 2009, Page:567--578,
28.

Preparation and biodistribution of 99mTc-IgG-HYNIC in normal rats


Authors: Rajabifar, Saeed and Akhlaghi, Mehdi and Jalilian, Amir R and Bolourinovin, Fateme and Maashkar, Behbood and Talebimehrdar, Mahbobe and Ghafouri, Mahdieh
Nukleonika, Vol.54, Year. 2009, Page:279--284,
29.

Development of 111In labeled insulin for receptor imaging/therapy


Authors: Jalilian, Amir and Garousi, J and Akhlaghi, M and Rowshanfarzad, P
Journal of radioanalytical and nuclear chemistry, Vol.279, Year. 2009, Page:791--796,
30.

Preclinical studies of [61Cu] ATSM as a PET radiopharmaceutical for fibrosarcoma imaging


Authors: Jalilian, Amir R and Rostampour, Nima and Rowshanfarzad, Pejman and Shafaii, Kamaleddin and Kamali-Dehghan, Mohsen and Akhlaghi, Mehdi
Acta pharmaceutica, Vol.59, Year. 2009, Page:45--55,
31.

Preparation and biological evaluation of [61Cu] bleomycin complex as a possible PET radiopharmaceutical in normal and fibrosarcoma-bearing animals


Authors: Jalilian, Amir R and Zandi, Hassan and Sardari, Daryoush and Akhlaghi, Mehdi and Kamali-Dehghan, Mohsen and Shafaei, Kamaleddin and Majdabadi, Abbas
Nukleonika, Vol.54, Year. 2009, Page:135--141,
32.

Evaluation of a [67Ga]-thiosemicarbazone complex as tumor imaging agent


Authors: Jalilian, Amir R and Mehdipour, Pegah and Akhlaghi, Mehdi and Yousefnia, Hassan and Shafaii, Kamaledin
Scientia Pharmaceutica, Vol.77, Year. 2009, Page:343--354,
33.

Production of copper-64 diacetyl-bis (N4-methylthiosemicarbazone) for therapeutic purposes


Authors: Jalilian, AR and Sabet, M and Rowshanfarzad, P and Kamali-Dehghan, M and Akhlaghi, M and Mirzaii, M and others
World J Nucl Med, Vol.7, Year. 2008, Page:166--171,
35.

Biological evaluation of [18F]-nifedipine as a novel PET tracer for L-type calcium channel imaging


Authors: Sadeghpour, Hossein and Jalilian, Amir R and Akhlaghi, Mehdi and Shafiee, Abbas and Mirzaii, Mohammad and Miri, Ramin and Saddadi, Fariba
Nukleonika, Vol.53, Year. 2008, Page:151--154,
36.

Radiosynthesis of dimethyl-2-[18F]-(fluoromethyl)-6-methyl-4-(2-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate for L-type calcium channel imaging


Authors: Sadeghpour, Hossein and Jalilian, Amir Reza and Shafiee, Abbas and Akhlaghi, M and Miri, R and Mirzaei, M
Radiochimica Acta, Vol.96, Year. 2008, Page:849--854,
37.

Determination of [201 Tl] Tl (III) in [201 Tl] TlCl solutions using HPLC


Authors: Akhlaghi, M and Kamalidehghan, M and Jalilian, AR and Shadanpoor, N
Applied Radiation and Isotopes, Vol.66, Year. 2008, Page:479--481,
38.

Preparation and evaluation of [61Cu]-thiophene-2-aldehyde thiosemicarbazone for PET studies


Authors: Jalilian, Amir R and Nikzad, Mirsaeed and Zandi, Hassan and Kharat, Ali Nemati and Rowshanfarzad, Pejman and Akhlaghi, Mehdi and Bolourinovin, Fatemeh
Nuclear Medicine Review, Vol.11, Year. 2008, Page:41--47,
39.

Preparation, quality control and biodistribution studies of two [111In]-rituximab immunoconjugates


Authors: Jalilian, Amir R and Sardari, Darush and Kia, Leila and Rowshanfarzad, Pejman and Garousi, Javad and Akhlaghi, Mehdi and Shanehsazzadeh, Saeed and Mirzaii, Mohammad
Scientia Pharmaceutica, Vol.76, Year. 2008, Page:151,
40.

Preparation and evaluation of [67Ga]-DTPA-$\beta$-1--24-corticotrophin in normal rats


Authors: Jalilian, AR and Shanehsazzadeh, S and Akhlaghi, M and Garoosi, J and Rajabifar, S and Tavakoli, MB
Radiochimica Acta, Vol.96, Year. 2008, Page:435--439,
41.

Preparation and biodistribution of [67Ga]-DTPA-gonadorelin in normal rats


Authors: Jalilian, Amir R and Shanehsazzadeh, S and Akhlaghi, M and Garousi, J and Rajabifar, S and Tavakoli, MB
Journal of radioanalytical and nuclear chemistry, Vol.278, Year. 2008, Page:123,
42.

Preparation and biodistribution of [111In]-rHu Epo for erythropoietin receptor imaging


Authors: Sadeghpour, H and Jalilian, A and Akhlaghi, M and Kamali-Dehghan, M and Mirzaii, M and Shafiee, A
Journal of radioanalytical and nuclear chemistry, Vol.278, Year. 2008, Page:117--122,
43.

Radiosynthesis of a 123I-labeled clorgiline derivative for MAO-A imaging


Authors: Jalilian, Amir R and Akhlaghi, Mehdi and Mirzaii, Mohammad and Aslani, Gholamreza and Rajamand, Amir A and Fateh, Behrooz and Kamalimoghadam, Kiomars
Journal of Labelled Compounds and Radiopharmaceuticals, Vol.50, Year. 2007, Page:424,
44.

Production and biological evaluation of [201TI (III)] bleomycin


Authors: Jalilian, Amir R and Aboudzadeh, Reza and Akhlaghi, Mehdi and Shirazi, Behrooz and Moradkhani, Sedighe and Salouti, Mohamad and Karimian, Alireza and Babaii, Mohammad H and Raisali, Gholamreza
Journal of Labelled Compounds and Radiopharmaceuticals, Vol.50, Year. 2007, Page:556,
45.

Preparation and biodistribution of [67Ga]-insulin for SPECT purposes


Authors: Jalilian, Amir R and Garousi, Javad and Gholami, Ebrahim and Akhlaghi, Mehdi and Rajabifar, S and others
Nukleonika, Vol.52, Year. 2007, Page:145--151,
46.

Experimental production and initial imaging of [18F]-14-Fluoro-6-thia-heptadecanoic acid ([18F]-FTHA) for myocardial performance [Persian]


Authors: Jalilian, Amir Reza and Akhlaghi, Mehdi and Saddadi, Fariba and Mirzaie, Mohammad and Karimian, Alireza and Pouladi, Mehraban and Yari Kamrani, Yousef and Moradkhani, Sedigheh and Shadanpour, Nami
Iranian Journal of Nuclear Medicine, Vol.14, Year. 2006, Page:35--41,
47.

Production and biological evaluation of [\^


Authors: Jalilian, Amir R and Akhlaghi, Mehdi and Mirzaii, Mohammad and Karimian, Alireza R
Nuclear Medicine Review, Vol.9, Year. 2006, Page:108,
48.

Optimization of the production of [61Cu] Diacetyl-bis (N4-methylthiosemicarbazone) for PET studies


Authors: Jalilian, AR and Sabet, M and Rowshanfarzad, P and Kamali-Dehghan, M and Akhlaghi, M and Mirzaii, M
Journal of radioanalytical and nuclear chemistry, Vol.269, Year. 2006, Page:147--154,
49.

[201Tl](III)-bleomycin for tumor imaging


Authors: Jalilian, AR and Akhlaghi, M and Shirazi, B and Aboudzadeh, R and Raisali, Gholamreza and Salouti, M and Babaii, M
Radiochimica Acta, Vol.94, Year. 2006, Page:453--459,
50.

Development of 111In-DTPA-human polyclonal antibody complex for long-term inflammation/infection detection


Authors: Jalilian, A and Rowshanfarzad, Pejman and Shafaii, Kamaleddin and Kamali-Dehghan, Mohsen and Moafian, Jamshid and Akhlaghi, Mahdi and Babaii, Mohammad and Rajabifar, Saeed and Mirzaii, Mohammad
Nukleonika, Vol.50, Year. 2005, Page:91--96,
51.

Production and quality control of 66Ga as a PET radioisotope


Authors: Rowshanfarzad, P and Jalilian, AR and Sabet, M and Akhlaghi, M
Iran. J. Radiat. Res, Vol.2, Year. 2004, Page:149--158,

Farsi

1.

، تهيه و بررسي زيستي نانوذرات ابر پارامغناطيسي اكسيد آهن نشان‌دار شده با گاليم-67 در موش صحرايي سالم


Authors: Jalilian, AR and Panahifar, A and Mahmoudi, M and Akhlaghi, M and Simchi, A
مجله علوم و فنون هسته ای, Vol.50, Year. 2010, Page:29-36,
2.

Determination of Kryptofix 2.2. 2 concentration in [18F] FDG radiopharmaceutical


Authors: AKHLAGHI, MAHDI and Jalilian, Amir R
مجله علوم و فنون هسته ای, Year. 2008,
3.

Selective extraction and separation of trace amounts of cobalt-57 from nickel


Authors: Akhlaghi, MAHDI and Rowshan Farzad, P
Journal of Nuclear Science and Technology, Year. 2007, Page:27--35,
4.

Production and quality control of sodium fluoride (Na 18 F) and its distribution in rates lesions as PET radiopharmaceutical for bone scan


Authors: Akhlaghi, MAHDI and Mirzaii, M and Jalilian, AMIR REZA and Shadanpoor, N and Moradkhani, S and Saddadi, F and Mostaan, M and Aslani, GR and Ensaf, MR
Journal of Nuclear Science and Technology, Year. 2006, Page:27--33,
1.

HPLC, GC, RTLC, Spectrometry, FT-IR, UV-Vis


2.

Quality Control of Radiopharmaceuticals


3.

cyclotron Operation, radioisotope production


4.

Radiolabeling


5.

Synthesis of Organic materials


1. ساخت نانوذرات با مدولیته تصویربرداری(PET) و درمان (شیمی درمانی)
2. ساخت نانوذرات با مودالیته چندگانه برای تصویربرداری MRIو PET
3. سنتز ترکیبات آلی و نشاندار سازی آنها با رادیوایزوتوپها(\PET and SPECT)
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