Tehran University of Medical Sciences
Synthesis and analgesic activity of 2-phenoxybenzoic acid and N-phenylanthranilic acid hydrazides.
Authors: Almasirad A , Hosseini R , Jalalizadeh H , Rahimi-Moghaddam Z , Abaeian N , Janafrooz M , Abbaspour M , Ziaee V , Dalvandi A , Shafiee A ,
Biological & pharmaceutical bulletin , Vol., No. 1347-5215 (Electronic) , 20060606 ,Page:0
A series of 2-phenoxybenzoic acid and N-phenylanthranilic acid hydrazides were synthesized and evaluated for their analgesic activities. Several compounds were significantly more potent than mefenamic acid and diclofenac sodium in abdominal constriction and formalin tests.