Tehran University of Medical Sciences
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Abbas Shafiee

Stereoselective synthesis and antifungal activity of (Z)-trans-3-azolyl-2-methylchromanone oxime ethers.


Authors: Emami S , Falahati M , Banifatemi A , Shafiee A ,
Bioorganic & medicinal chemistry , Vol., No. 0968-0896 (Print) , 20041022 ,Page:0
A series of (Z)-trans-3-azolyl-2-methylchromanone oxime ethers were stereoselectively synthesized and tested for in vitro antifungal activity. Many of these derivatives exhibit high activity against Candida albicans, Saccharomyces cerevisiae, Aspergillus niger, and Microsporum gypseum.