Tehran University of Medical Sciences
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Abbas Shafiee

Potential long-acting contraceptive agents: esters and ethers of testosterone with alpha- and/or beta-chain branching.


Authors: Herz JE , Torres JV , Murillo A , Cruz S , Shafiee A , Vosooghi M , Sotheeswaran S , Gunatilaka AA ,
Steroids , Vol., No. 0039-128X (Print) , 19861114 ,Page:0
The synthesis of ten esters and two ethers of testosterone (17 beta-hydroxyandrost-4-en-3-one) is described. All these possess some form of alpha - and/or beta - substitution in the ester/ether side-chain. The work was undertaken in order to evaluate the long-acting antifertility effect of such compounds in males.