Tehran University of Medical Sciences
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Abbas Shafiee

Long-acting contraceptive agents: norethisterone esters of arylcarboxylic acids.


Authors: Wan AS , Ngiam TL , Leung SL , Go ML , Heng PW , Natarajan PN , Shafiee A , Vossoghi M , Savabi F , Francisco CG , et al. ,
Steroids , Vol., No. 0039-128X (Print) , 19840214 ,Page:0
The synthesis of esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxy-estr-4-en-3-one) with acids containing a benzene ring is described, two methods of esterification being compared in terms of yield and convenience. The activities of these esters as long-acting contraceptive agents have been evaluated.