Tehran University of Medical Sciences
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Mahmood Alimohammadi

Application of response surface methodology for modeling and optimization of Bacillus subtilis spores inactivation by the UV/persulfate process


Authors: Zahra Sabeti, Mahmood Alimohammadi, Samira Yousefzadeh, Hassan Aslani, Maryam Ghani, Ramin Nabizadeh
Water Science and Technology: Water Supply, Vol.16, No.4, 2016,Page:

Stronger disinfection techniques are required to inactivate Bacillus subtilis spores as surrogate microorganisms for Cryptosporidium parvum oocysts. In this study, the effects of UV and persulfate separately and also in combination were investigated on B. subtilis spore inactivation. Central composite design and response surface methodology were used to optimize target microorganism reduction. Contact time, initial pH, and persulfate dosage were considered as input experimental variables. Based on the design of the experiments, first and second order response surface models have been developed to correspond to the output response of