Tehran University of Medical Sciences
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Azadeh Ebrahim-Habibi

Contact Information
http://tums.ac.ir/faculties/aehabibi
Address: Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Fifth floor of Shariati Hospital, North Kar
Academic Rank
Professor
Research Center
Endocrinology and Metabolism Research Center
About
CV last edited on: 2017/26/08

1.

Postdoctoral fellowship


Institut für Pharmazeutische und Medizinische Chemie, Pharmacy , Düsseldorf, Germany, 2006-2007

Project title: Homology modeling of a glucosidase enzyme

Under supervision of Professor Hans-Dieter Hoeltje

2.

Ph.D


Biochemistry, University of Tehran , Tehran, Iran, Thesis Title:Chemical modification of alpha-amylase
Supervisor:Professor Mohsen Nemat-Gorgani
3.

Pharm D


Pharmacy, School of Pharmacy of the Azad University, Tehran, Iran, 1997
1.

Persian


Speaking: Native, Reading: Native, Writing: Native
2.

French -close to native


Speaking: Native, Reading: Native, Writing: Native
3.

English-written, read, spoken


4.

German -Zertifikat Deutsch, grade: 1


1.

Selected as best 2004 Biochemistry Ph.D. candidate of IBB


2004,
2.

Ranked second between fellow students of the Pharm.D. program


1997,

Scientific Position

1.

Assistant Professor


Tehran University of Medical Sciences,
2.

Associate Professor


Tehran University of Medical Sciences, 2012

-

1.

Protein Structure


Ph.D, Science and Research Branch Aza,-.
2.

Enzymology


M.Sc. and Ph.D, Science and Research Branch Aza,-.
3.

Enzymes Mechanism of Action


Ph.D, Science and Research Branch Aza,-.
4.

Introduction to Medicinal Chemistry


M.Sc, Science and Research Branch Aza,-.
5.

Special Topics in Biochemistry


M.Sc, Science and Research Branch Aza,-.

Supervisor

1.

Molecular modeling and in vitro study on proposed lipase inhibitors


,
Biochemistry, M.Sc. Thesis, 2011
2.

Study on the effects of some phenol and purine compounds on alpha-amylase activity using a direct kinetic assay


,
Biochemistry, M.Sc. Thesis, 2011
3.

Comparative study of organic solvents effect on insulin aggregation


,
Biochemistry, M.Sc. Thesis., 2010
4.

Biotechnology, M.Sc. Thesis


,
Biochemistry, M.Sc. Thesis , 2010
5.

Study on the effect of natural compounds on amyloid formation of insulin.


,
Biotechnology, M.Sc. Thesis, 2010
6.

Chemical modification of the lysine residue of bovine insulin and studying modified protein structure and aggregation in vitro


,
Biochemistry, M.Sc. Thesis, 2009
7.

Molecular modeling studies on bacterial acetate kinase: studying the active site and design of inhibitors


,
Biochemistry, M.Sc. Thesis, 2009
8.

Study on the inhibitory effect of polyphenolic compounds on alpha-amylase enzymes from Aspergillus oryzae, Sus scrofa and human


,
Biochemistry, M.Sc. Thesis, 2008
9.

Investigation of the effect of several natural compounds on the activity of alpha amylase and level of blood sugar in diabetic


,
Ph.D, Biochemistry, Ph.D. Thesis, 2010

Advisor/Consulter

1.

Advisor for 18 M.Sc. theses (Biochemistry,Biophysics) between


,
2008-2011
2.

A comparative study on amyloid fibril formation in apo and holo bovine carbonic anhydrase II


,
Ph.D, Biochemistry, Ph.D. Thesis, 2012
3.

Induction and characterization of intermediate structures in glutamate dehydrogenase leading to its aggregation.


,
Ph.D, Biochemistry, Ph.D. Thesis, 2008
4.

duction of amyloid aggregation of bovine alpha-chymotrypsin and biochemical and biophysical characterization of its intermediate


,
Ph.D, Biochemistry, Ph.D. Thesis, 2007

English

1.

-Book Chapter-Pheochromocytoma –A New View of the Old Problem Edited By: Jose Fernando Martin


Authors: Shirin Hasani-Ranjbar, Azadeh Ebrahim-Habibi and Bagher Larijani
Publisher: InTech, 2011, Original

Papers

English

1.

Complexation of nicotinic acid with first generation poly (amidoamine) dendrimers: A microscopic view from density functional theory


Authors: Farideh Badalkhani-Khamseh, Aidin Bahrami, Azadeh Ebrahim-Habibi, Nasser L Hadipour
Chemical Physics Letters, Vol.684, Year. 2017, Page:103-112,
2.

Therapeutic protein deimmunization by T‐cell epitope removal: antigen‐specific immune responses in vitro and in vivo


Authors: Saeme Asgari, Azadeh Ebrahim‐Habibi, Mehdi Mahdavi, Mohammad Choopani, Hasan Mirzahoseini
Apmis, Vol.125, No.6, Year. 2017, Page:544-552,
3.

Investigation of thymol effect on learning and memory impairment induced by intrahippocampal injection of amyloid beta peptide in high fat diet-fed rats


Authors: Masoumeh Asadbegi, Parichehreh Yaghmaei, Iraj Salehi, Alireza Komaki, Azadeh Ebrahim-Habibi
Metabolic Brain Disease, Vol.32, No.3, Year. 2017, Page:827-839,
4.

Turmeric effect on subcutaneous insulin-induced amyloid mass: an in vivo study


Authors: Raheleh Kheirbakhsh, Maryam Chinisaz, Saeid Amanpour, Shahab Amini, Saeed Khodayari, Hamid Khodayari, Aydin Dilmaghanian, Mahnaz Haddadi, Azadeh Ebrahim-Habibi
Drug and chemical toxicology, Vol.40, Year. 2017, Page:1-6,
5.

Characterization of surface binding sites in glycoside hydrolases: A computational study


Authors: Samaneh Samaei‐Daryan, Bahram Goliaei, Azadeh Ebrahim‐Habibi
Journal of Molecular Recognition, Year. 2017,
6.

Structure and function of anhydride-modified forms of human insulin: In silico, in vitro and in vivo studies


Authors: Maryam Chinisaz, Azadeh Ebrahim-Habibi, Ahmad-Reza Dehpour, Parichehreh Yaghmaei, Kazem Parivar, Ali Akbar Moosavi-Movahedi
European Journal of Pharmaceutical Sciences, Vol.96, Year. 2017, Page:342-350,
7.

Amyloid-like aggregates formation by bovine apo-carbonic anhydrase in various alcohols: A comparative study


Authors: Ali Es-haghi, Azadeh Ebrahim-Habibi, Marjan Sabbaghian, Mohsen Nemat-Gorgani
International journal of biological macromolecules, Vol.92, Page:573-580,
8.

Bis (indolyl) phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme


Authors: Hassan Ramshini, Benedetta Mannini, Kaveh Khodayari, Azadeh Ebrahim-Habibi, Azam Sadat Moghaddasi, Reza Tayebee, Fabrizio Chiti
European journal of medicinal chemistry, Vol.124, Year. 2016, Page:361-371,
9.

Effect of trans-chalcone on atheroma plaque formation, liver fibrosis and adiponectin gene expression in cholesterol-fed NMRI mice


Authors: Leyla Karkhaneh, Parichehreh Yaghmaei, Kazem Parivar, Majid Sadeghizadeh, Azadeh Ebrahim-Habibi
Pharmacological Reports, Vol.68, No.4, Year. 2016, Page:720-727,
10.

Benzothiazole Thioflavin T improves obesity-related symptoms in mice


Authors: Fatemeh Jalalvand, Mahsa M Amoli, Parichehreh Yaghmaei, Masoud Kimiagar, Azadeh Ebrahim-Habibi
Periodicum Biologorum, Vol.118, No.2, Year. 2016,
11.

Acarbose and the thermal aggregation of Bacillus amyloliquefaciens alpha‐amylase (BAA): protective effect of an inhibitor


Authors: Hanieh Shojaee, Marjan Sabbaghian, Azadeh Ebrahim‐Habibi
Journal of Chemical Technology and Biotechnology, Vol.91, No.5, Year. 2016, Page:1397-1402,
12.

Neuroprotective effects of metformin against Aβ-mediated inhibition of long-term potentiation in rats fed a high-fat diet


Authors: Masoumeh Asadbegi, Parichehreh Yaghmaei, Iraj Salehi, Azadeh Ebrahim-Habibi, Alireza Komaki
Brain research bulletin, Year. 2016,
13.

Rational design of stable and functional hirudin III mutants with lower antigenicity


Authors: Saeme Asgari, Hasan Mirzahoseini, Morteza Karimipour, Hamze Rahimi, Azadeh Ebrahim-Habibi
Biologicals,
14.

Bacterial expression and characterization of an active recombinant lipase A from Serratia marcescens with truncated C-terminal region


Authors: Mohammadi M, Sepehrizadeh Z, Ebrahim-Habibi A, Shahverdi AR, Faramarzi MA, Setayesh N
Journal of Molecular Catalysis B: Enzymatic,
15.

Acarbose versus trans-chalcone : comparing the effect of two glycosidase inhibitors on obese mice


Authors: Jalalvand F, Amoli MM, Yaghmei P, Kimiagar M, Ebrahim-Habibi A
Arquivos Brasileiros de Endocrinologia & Metabologia,
16.

Inhibition of amyloid fibril formation and cytotoxicity by a chemical analog of curcumin as a stable inhibitor


Authors: Ramshini H., Mmohammad-Zadeh M., Ebrahim-Habibi A
International Journal of Biological Macromolecules,
17.

UV spectrophotometric determination and validation of hydroquinone in liposome


Authors: Khoshneviszadeh R., Bazzaz BSF., Housaindokht MR, Ebrahim-Habibi A., Rajabi O.
Iranian Journal of Pharmaceutical Research, Vol.14, No.2, Year. 2015, Page:473-478,
18.

Injection of insulin amyloid fibrils in the hippocampus of male Wistar rats : report on memory impairment and formation of amyloid plaques


Authors: Kheirbakhsh R, Chinisaz M, Khodayari S, Amanpour S, Dehpour AR, Muhammadnejad A, Larijani B, Ebrahim-Habibi* A
Neurological Sciences ,
19.

. Segregation of a novel homozygous 6 nucleotide deletion in GLUT2 gene in a Fanconi-Bickel syndrome family.


Authors: Abbasi F, Azizi F, Javaheri M, Mosallanejad A, Ebrahim-Habibi A, Ghafouri-Fard S
Gene, Vol.557, No.1, Year. 2015, Page:103-105,
20.

Effect of neohesperidin dihydrochalcone on the activity and stability of alpha-amylase: a comparative study on bacterial, fungal, and mammalian enzymes


Authors: Kashani-Amin E, Ebrahim-Habibi A*, Larijani B, Moosavi-Movahedi AA
Journal of Molecular Recognition,
21.

Structural stability of myoglobin and glycomyoglobin: A comparative molecular dynamics simulation study


Authors: Alizadeh-Rahrovi J, Shayesteh A*, Ebrahim-Habibi *A
Journal of Biological Physics,
22.

Thioflavin T effect in diabetic Wistar rats: Reporting the antihyperglycemic property of an amyloid probing dye


Authors: Najafian, M., Amini, S., Dehestani, B., Parivar, K., Ebrahim-Habibi, A
Pharmacological Reports, Vol.67, Year. 2015, Page:364-369,
23.

Interaction of Aβ(25-35) Fibrillation Products with Mitochondria: Effect of Small-Molecule Natural Products


Authors: Ghobeh M, Ahmadian S, Meratan AA, Ebrahim-Habibi A, Ghasemi A, Shafizadeh M, Nemat-Gorgani M
Biopolymers: Peptide Science , Vol.102, No.6, Year. 2014, Page:473-476,
24.

A novel missense mutation in oncostatin m receptor Beta causing primary localized cutaneous amyloidosis


Authors: Saeedi M, Ebrahim-Habibi A, Haghighi A, Zarrabi F, Amoli MM, Robati RM
Biomed Res Int, Year. 2014,
25.

Applications of molecular modeling in endocrinology


Authors: Ebrahim-Habibi A., Larijani B
Iranian Journal of Public Health, Vol.43, Year. 2014,
26.

A new missense mutation in FGF23 gene in a male with hyperostosis-hyperphosphatemia syndrome (HHS)


Authors: Abbasi, F., Ghafouri-Fard, S., Javaheri, M., Dideban, A., Ebrahimi, A., Ebrahim-Habibi, A
Gene, Vol.542, No.2, Year. 2014, Page:269-271,
27.

A molecular modeling study on full length insulin: insight into initial events of amyloid formation


Authors: Chinisaz M, Larijani B, Ebrahim-Habibi *A
Structural Chemistry, Year. In Press,
28.

Generating local amyloidosis in mice by subcutaneous injection of human insulin amyloid


Authors: Chinisaz M, Ebrahim-Habibi A, Yaghmaei P, Parivar K, Dehpour A-R
Experimental and Therapeutic Medicine Journal, Year. Accepted,
29.

Ectopic Cushing syndrome associated with thymic carcinoid tumor as the first presentation of MEN1 syndrome-report of a family with MEN1 gene mutation


Authors: Hasani-Ranjbar S, Rahmanian M, Ebrahim-Habibi A, Soltani A, Soltanzade A, Mahrampour E, Amoli MM
Familial Cancer, Year. Accepted,
30.

Production of insulin amyloid nanofibrils in organic solvents: a comparative study


Authors: Nemati-Lay M., Nemati-Lay E., Larijani B., Ebrahim-Habibi *A
Minerva Biotecnologica, Year. Accepted,
31.

Silymarin effect on amyloid ß plaque accumulation and gene expression of APP in an Alzheimer’s disease rat model


Authors: Yaghmaei P.*, Azarfar K., Dezfulian M. , Ebrahim-Habibi *A
DARU, Vol.22:24, Year. 2014,
32.

Amyloid formation and inhibition of an all-beta protein: a study on fungal polygalacturonase


Authors: Chinisaz M, Ghasemi A, Larijani B, Ebrahim-Habibi* A
Journal of Molecular Structure , Vol.1059, Year. 2014, Page:94–100,
33.

Indole and trans–chalcone attenuate amyloid beta plaque accumulation in male Wistar rat: in vivo effectiveness of two anti-amyloid scaffolds


Authors: Yaghmaei P, Kheirbakhsh R, Dezfulian M, Haeri-Rohani A, Larijani B, Ebrahim-Habibi *A
Archives Italiennes de Biologie , Vol.151, No.3, Year. 2013, Page:106-113,
34.

Targeting acetate kinase: inhibitors as potential bacteriostatics


Authors: Asgari S., Shariati * P., Ebrahim-Habibi* A.
Journal of Microbiology and Biotechnology, Vol.23, Year. 2013, Page:1544-1553 ,
35.

How curcumin affords effective protection against amyloid fibrillation in insulin


Authors: Rabiee A., Ebrahim-Habibi *A, Ghasemi A., Nemat-Gorgani*M..
Food and Function , Vol.4, Year. 2013, Page:1474-1480,
36.

Neohesperidin dihydrochalcone: presentation of a small molecule activator of mammalian alpha- amylase as an allosteric effector


Authors: Kashani-Amin E, Larijani B,Ebrahim-Habibi *A
FEBS Letters, Vol.587, No.6, Year. 2013, Page:652-8,
37.

Reflection on design and testing of pancreatic alpha-amylase inhibitors: an in silico comparison between rat and rabbit enzyme models


Authors: Khalil-Moghaddam S, Ebrahim-Habibi A, Pasalar P, Yaghmaei P, Hayati-Roodbari N
DARU Journal of Pharmaceutical Sciences , Vol.20, No.77, Year. 2012,
38.

Heme binding site in apomyoglobin may be effectively targeted with small molecules to control aggregation


Authors: Azami-Movahed M, Shariatizi S, Sabbaghian M, Ghasemi A, Ebrahim-Habibi* A, Nemat-Gorgani* M
The international journal of biochemistry & cell biology, Vol.45, Year. 2013, Page: 299– 307 ,
39.

Maternal zinc intake of Wistar rats has a protective effect in the alloxan-induced diabetic offspring


Authors: Yaghmaei* P, Esfahani-Nejad H, Ahmadi R, Hayati-Roodbari N, Ebrahim-Habibi *A
Journal of Physiology and Biochemistry, Year. 2012,
40.

Xanthine derivatives as activators of alpha-amylase: Hypothesis on a link with the hyperglycemia induced by caffeine


Authors: Kashani-Amin E, Yaghmaei P, Larijani B, Ebrahim-Habibi* A
Obesity Research & Clinical Practice, Year. 2012,
41.

Response surface methodology for optimizing the bovine serum albumin fibrillation


Authors: Arasteh A, Habibi-Rezaei M, Ebrahim-Habibi A, Moosavi-Movahedi AA
The Protein Journal, Vol.31, No.6, Year. 2012, Page:457-465,
42.

Thermal disaggregation of type B yeast hexokinase by indole derivatives: a mechanistic study


Authors: Ramshini H, Ebrahim-Habibi A
International Journal of Biological Macromolecules, Vol.50, No.5, Year. 2012, Page:1260-1266,
43.

Amyloid fibrillation in native and chemically-modified forms of carbonic anhydrase II: Role of surface hydrophobicity.


Authors: Es-haghi A., Shariatizi S., Ebrahim-Habibi A., Nemat-Gorgani M
Biochimica et Biophysica Acta, Vol.1824, No.3, Year. 2012 , Page:468-477,
44.

Detection of KCNJ11 Gene Mutations in a Family with Neonatal Diabetes: Implications for Therapeutic Management of Family Members with Long-Standing Disease


Authors: Abbasi F, Saba S, Ebrahim-Habibi* A, Sayahpour FA, Amiri P, Larijani B, Amoli* MM
Molecular Diagnosis & Therapy, Vol.16, No.2, Year. 2012, Page:109-114,
45.

Trans-chalcone: a novel small molecule inhibitor of mammalian alpha-amylase


Authors: Najafian M, Ebrahim-Habibi A*, Hezareh N, Yaghmaei P, Parivar K, Larijani B)
Molecular Biology Reports, Vol.38, Year. 2011, Page:1617-1620,
46.

Novel mutations of wolframin: a report with a look at the protein structure


Authors: A, Ebrahim-Habibi A*, Abbasi F*, Amoli M, Sayahpour FA, Larijani B
Clinical Genetics, Vol.79, Year. 2011, Page:96-99,
47.

new frameshift MEN1 gene mutation associated with familial malignant insulinomas.


Authors: Hasani-Ranjbar S, Amoli MM, Ebrahim-Habibi A, Gozashti MH, Khalili N, Sayyahpour FA, Hafeziyeh J, Soltani A, Larijani B
Familial Cancer, Vol.10, Year. 2011, Page:343-348,
48.

-Effects of Sucrose and Trehalose on Stability, Kinetic Properties, and Thermal Aggregation of Firefly Luciferase


Authors: Rasouli S, Hosseinkhani S, Yaghmaei P, Ebrahim-Habibi A.
Applied Biochemistry and Biotechnology., Vol.165, No.2, Year. 2011, Page:572-82,
49.

Prevention of thermal aggregation of an allosteric protein by small molecules: Some mechanistic insights


Authors: Sabbaghian M, Ebrahim-Habibi A, Hosseinkhani S, Ghasemi A, Nemat-Gorgani M
International Journal of Biological Macromolecules, Vol.49, No.4, Year. 2011, Page:806-13,
50.

Benzofuranone derivatives as effective small molecules related to insulin amyloid fibrillation: a structure-function study


Authors: Rabiee A, Ebrahim-Habibi A*, Navidpour L, Morshedi D, Ghasemi A, Sabbaghian M, Nemati-Lay M, Nemat-Gorgani* M
Chemical Biology and Drug Design, Vol.78, No.4, Year. 2011, Page:659-66 ,
51.

-Immobilization of acetylcholinesterase in nanofibrous PVA/BSA membranes by electrospinning


Authors: Moradzadegan A., Ranaei-Siadat S-O., Ebrahim-Habibi A., Barshan-Tashnizi M., Jalili R., Torabi S-F, Khajeh K
Engineering in Life Sciences, Vol.10, Year. 2010, Page:57-64,
52.

Fibrillation of alpha-lactalbumin: effect of crocin and safranal, two natural small molecules from Crocus sativus.


Authors: Ebrahim-Habibi M-B., Amininasab M., Ebrahim-Habibi A., Sabbaghian M., Nemat-Gorgani M.
Biopolymers, Vol.93, Year. 2010, Page:854-865,
53.

Protein-protein interactions leading to aggregation: perspectives on mechanism,significance and control


Authors: Ebrahim-Habibi A., Morshedi D., Rezaei-Ghaleh N., Sabbaghian M., Nemat-Gorgani M
Journal of the Iranian Chemical Society, Vol.7, Year. 2010, Page:521-544,
54.

Chemical modification of lysine residues in lysozyme may dramatically influence its amyloid fibrillation


Authors: Morshedi D., Ebrahim-Habibi A., Moosavi-Movahedi A., Nemat-Gorgani M
Biochimica et Biophysica Acta, Vol.1804, Year. 2010, Page:714-722,
55.

Core structure of flavonoids precursor as an antihyperglycemic and antihyperlipidemic agent: an in vivo study in rats


Authors: Najafian M, Ebrahim-Habibi A., Yaghmaei P, Parivar K, Larijani B
Acta Biochimica Polonica , Vol.57, Year. 2010, Page:553-560,
56.

Amyloidogenic potential of alpha-chymotrypsin in different conformational states


Authors: . Rezaei-Ghaleh N., Zweckstetter M. ,Morshedi D., Ebrahim-Habibi A., Nemat-Gorgani M.
Biopolymers, Vol.91, Year. 2009, Page:28-36,
57.

Thermal aggregation of a model allosteric protein in different conformational states.


Authors: Sabbaghian M.,Ebrahim-Habibi A., Nemat-Gorgani M
International Journal of Biological Macromolecules, Vol.44, Year. 2009, Page:156-162,
58.

Mutation screening of VHL gene in a family with malignant bilateral pheochromocytoma: from isolated familial pheochromocytoma to von Hippel-Lindau disease


Authors: Hasani-Ranjbar S, Amoli MM, Ebrahim-Habibi A,Haghpanah V, Hejazi M, Soltani A, Larijani B
Familial Cancer, Vol.8, Year. 2009, Page:465-471.,
59.

Thermal aggregation of α-chymotrypsin: Role of hydrophobic and electrostatic interactions


Authors: Rezaei-Ghaleh N., Ramshini H., Ebrahim-Habibi A.,Moosavi-Movahedi AA. , Nemat-Gorgani M.
Biophysical Chemistry, Vol.132, Year. 2008, Page:23-32,
60.

Thermally induced changes in the structure and activity of yeast hexokinase B


Authors: Ramshini H., Rezaei-Ghaleh N., Ebrahim-Habibi A., Saboury AA, Nemat-Gorgani M.
Biophysical Chemistry, Vol.137, Year. 2008, Page:88-94.,
61.

-Role of electrostatic interactions in 2,2,2-trifluoroethanol-induced structural changes and aggregation of α-chymotrypsin


Authors: Rezaei-Ghaleh N., Ebrahim-Habibi A., Moosavi-Movahedi AA.,Nemat-Gorgani M
Archives of Biochemistry and Biophysics, Vol.457, Year. 2007, Page:160-169,
62.

Effect of polyamines on the structure, thermal stability and 2,2,2-trifluoroethanol-induced aggregation of α-chymotrypsin


Authors: Rezaei-Ghaleh N., Ebrahim-Habibi A.,Moosavi-Movahedi AA., Nemat-Gorgani M.
International Journal of Biological Macromolecules, Vol.41, Year. 2007, Page:597-604,
63.

Inhibition of amyloid fibrillation of lysozyme by indole derivatives : possible mechanism of action.


Authors: Morshedi D.,Rezaei-Ghaleh N., Ebrahim-Habibi A., Ahmadian S., Nemat-Gorgani M.
FEBS Journal , Vol.274, Year. 2007, Page:6415–6425,
64.

Thermostabilization of Bacillus amyloliquefaciens alpha-amylase by chemical crosslinking


Authors: Ebrahim-Habibi A. ,Khajeh K., Naderi-Manesh H., Ranjbar B., Nemat-Gorgani M
Journal of Biotechnology, Vol.123, Year. 2006, Page:434-442,
65.

-Chemical modification of lysine residues in Bacillus licheniformis alpha-amylase: conversion of an endo- to an exo-type enzyme.


Authors: Ebrahim-Habibi A., Khajeh K., Nemat-Gorgani M.
Journal of Biochemistry and Molecular Biology, Vol.37, Year. 2004, Page:642-647,
66.

Interaction of an intermediate structure of Bacillus subtilis alpha-amylase with alkyl-substituted sepharose 4B: a model of membrane translocation


Authors: Karbalaei-Heidari HR., Ebrahim Habibi A., Khajeh K.,Ranjbar B., Nemat-Gorgani M.
Applied Biochemistry and Biotechnology, Vol.117, Year. 2004, Page:123-32,
67.

Chemical modification of bacterial alpha-amylases: changes in tertiary structures and the effect of additional calcium


Authors: Khajeh K., Ranjbar B., Naderi-Manesh H., Ebrahim Habibi A., Nemat-Gorgani M
Biochimica et Biophysica Acta, Vol.1548, No.2, Year. 2001, Page:229-37,

Abstracts and Presentations

English

1.

Acylation of LYS residues prevents thermal aggregation of glutamate dehydrogenase


Date: June 2006-Type : Abstract, Journal: FEBS journal , No: 600, Suppl: 1, Volume: 273, others,
2.

Prevention of thermal aggregation of glutamate dehydrogenase by polyamines


Date: une 2006-Type : Abstract, Journal: FEBS journal , No: 597, Suppl: 1, Volume: 273, others,
3.

TFE-induced aggregation of alpha-chymotrypsin:involvement of hydrophobic and electrostatic interactions


Date: June 2006--Type : Abstract, Journal: FEBS journal , No: 585, Suppl: 1, Volume: 273, others,
4.

Heat-induced aggregation of a-chymotrypsin: role of hydrophobic and electrostatic Interactions


Date: July 2007 -Type : Abstract, Journal: FEBS journal, No: F1-149, p.302, Suppl: 1, Volume: 274, others,
5.

-Effect of amino acids on thermal aggregation of glutamate dehydrogenase


Date: July 2007 -Type : Abstract, Journal: FEBS journal, No: F1-50, p.277, Suppl: 1, Volume: 274, others,
6.

Chemical modification of Lys residues prevents TFE-induced aggregation of alpha-chymotrypsin


Date: July 2007-Type : Abstract, Journal: FEBS Journal, No: F1-49, p.277, Suppl: 1, Volume: 274, others,
7.

Inhibition of amyloid fibrillation of lysozyme by indole derivatives


Date: July 2007 -Type : Abstract, Journal: FEBS journal, No: F1-43, p.275, Suppl: 1, Volume: 274, others,
8.

The role of phosphate in thermal aggregation of yeast hexokinase II


Date: October 2007-Type : Abstract, Journal: Archives of Iranian Medicine, No: O841, (S271-272), Suppl: 1, Volume: 10, Issue: 4, others,
9.

Modification of lysine residues in lysozyme: Effects on amyloid fibrillation


Date: October 2007-Type : Abstract, Journal: Archives of Iranian Medicine, No: O839, (S271), Suppl: 1, Volume: 10, Issue: 4, others,
10.

Induction of amyloid fibril formation by alpha-chymotrypsin by two different methods


Date: October 2007-Type : Abstract, Journal: .Archives of Iranian Medicine, No: p754 (S243-244, Suppl: 1, Volume: 10, Issue: 4, others,
11.

Aggregation of glutamate dehydrogenase: role of allosteric effectors. Sabbaghian M.,


Date: October 2007-Type : Abstract, Journal: Archives of Iranian Medicine, No: p221 (S79), Suppl: 1, Volume: 10, Issue: 4, others,
12.

Prevention of thermal aggregation of alpha-chymotrypsin by acetylation of its lysine residues


Date: October 2007-Type : Abstract, Journal: Archives of Iranian Medicine, No: p150 (S61), Suppl: 1, Volume: 10, Issue: 4, others,
13.

Homology modelling of human Maltase enzyme and in silico characterization of its active site


Archives of Iranian Medicine
Date: October 2007-Type : Abstract, No: p420 (S141), Suppl: 1, Volume: 10, Issue: 4, others,
14.

An in silico study on the inhibitor selectivity of Cathepsin G


Date: October 2007-Type : Abstract, Journal: Archives of Iranian Medicine, No: p428 (S143-144), Suppl: 1, Volume: 10, Issue: 4, others,
15.

Modification of alpha-Chymotrypsin with Citraconic Anhydride: Changes in Structure and Stability


Date: 2008-Type : Abstract, Journal: Protein Science, Suppl: 1, Volume: 17, others,
16.

Investigation of Conformational Change of Glutamate Dehydrogenase in the Presence of TFE


Date: 2008-Type : Abstract, Journal: Protein Science, Suppl: 1, Volume: 17, others,
17.

Dramatic Enhancement of Lysozyme Fibrillogenesis by ATP


Date: 2008-Type : Abstract, Journal: Protein Science, Suppl: 1, Volume: 17, others,
18.

Formation of small soluble aggregates may be responsible for irreversible thermal denaturation of yeast hexokinase B


.FEBS Journal
Date: 2008-Type : Abstract, No: 195, Suppl: 1, Volume: 275, others,
19.

Thermal aggregation of Bacillus amyloliquefaciens alpha-amylase: effect of amino acids


Date: 2008-Type : Abstract, Journal: FEBS Journal, No: 189, Suppl: 1, Volume: 275, others,
20.

Inhibitors of insulin amyloid formation: an in silico study


Date: 2008-Type : Abstract, Journal: FEBS Journal, No: 165, Suppl: 1, Volume: 275, others,
21.

Flavonoids as potential antihyperglycemics: an in silico study of their alpha-amylase inhibitory mode.


Date: 2008-Type : Abstract, Journal: Drugs of the Future, No: 306-307, Suppl: A, Volume: 33, others,
22.

Molecular modelling studies on alpha-glucosidase interaction with inhibitors


Proceedings of the 2nd Iranian Conference on Bioinformatics
Date: 2008-Type : Abstract, Volume: 8, Issue: 9, others,
23.

Curcumin inhibits mammalian alpha-amylase


Date: 2009-Type : Abstract, Journal: Proccedings of VIII European Symposium of The Protein Society , others,
24.

Thioflavin T may influence fibrillation of proteins of different structural properties


Date: 2009-Type : Abstract, Journal: FEBS Journal , No: 155, Suppl: 1, Volume: 276, others,
25.

Synchronize fluorescence study of interaction between human lactoferrin as a carrier and lomefloxacin


Date: 2009-Type : Abstract, Journal: Journal of the Iranian Chemical Society,, No: S88-S89, Suppl: 1, Volume: 6, others,
26.

Investigation on the interaction between two different drugs (lomefloxacin and colchicines) and human serum albumin: A spectrosc


Date: 2009-Type : Abstract, Journal: Journal of the Iranian Chemical Society, No: 88, Suppl: 1, Volume: 6, others,
27.

Targeting acetate kinase: Inhibitors as potential bacteriostatics.Asgari S


Date: 2006-Type : Abstract, Journal: Journal of the Iranian Chemical Society, No: 87, Volume: 6, Issue: 1, others,
28.

-Design of new alpha-glucosidase inhibitors based on molecular modeling studies


Date: 2009-Type : Abstract, Journal: Journal of the Iranian Chemical Society, No: 90, Suppl: 1, Volume: 6, Issue: O-10, others,
29.

Molecular modeling studies on cholesterol esterase inhibitors: proposition of new ligands , and insight into possible additional


Date: 2010-Type : Abstract, Journal: 3rd Iranian Conference on Bioinformatics, Volume: 5-6, others,
30.

Proposal Of Novel Nad+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Inhibitors Based On A Molecular Modeling Study.


Date: 2010-Type : Abstract, Journal: Drugs of the Future, Suppl: Suppl.A, Volume: 35, others,
31.

Molecular Modeling Study on Palmitate Binding Site in Echovirus Coat Protein: Proposing an Antiviral Target


Larijani B.Proceedings of the 6th International Symposium on Health Informatics and Bioinformatics,(
Location: Izmir, Turkey,
Date: 2011-Type : Abstract, others,
32.

Thioflavin as a potential antidiabetic lead compound


Date: 2011-Type : Abstract, Journal: Journal of the Iranian Chemical Society, Suppl: 2, Volume: 8, others,
1.

Journal of Diabetes and Metabolic Disorders


2012- Editor,

Section Editor (Interdisciplinary Medicine)

1.

Iran Society of Biophysical Chemistry


Activity Type:عضو هیئت مدیره
2.

Iran Bioinformatics Society


Activity Type:Member
3.

Iran Endocrine Society


Activity Type:سایر
1. Enzymology, Protein Structure, Molecular Modeling
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